Indian Viagra (Sildenafil Citrate): Description and Advantages

Indian Viagra_ Description and Advantages

Viagra is a world-famous drug for men that improves erectile function, stabilizes potency, increases sexual intercourse. The remedy is prescribed to men who have signs of impotence.

The price of the original Viagra pills is quite high. Today, there is an analogue of the original – generic Indian Viagra. It has exactly the same properties and is designed according to the production scheme. The pills are easily tolerated and completely safe for the male body. But what are generic drugs and how does generic Viagra differ from its brand-name counterpart?

What should you know about generic drugs?

First of all, you need to understand the definitions. The range of medicines includes three names for each drug:

  • chemical;
  • international non-patented;
  • trade.

Any drug that contains one active substance has a chemical name (formula), which, however, is used only in scientific works and specialized professional literature due to its complexity. For example, here is the full chemical name of Viagra is 5-[2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1- methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, formula C22H30N6O4S. Obviously, it is not possible to use the chemical name in everyday life, and therefore each drug has a single and official international non-proprietary name. For Viagra (as well as all generics of Viagra), it will sound like “Sildenafil”. The chemical name is never indicated on the package (it can be found in the package insert or in the instructions for use, but the international non-patented is indicated in small letters under the trade name. The latter is also called the commercial or patented name. It is given by the manufacturer for the purpose of marketing positioning of its “creation.” The corporate name is chosen in such a way as to better be stored in the head of the potential consumer. Viagra is a vivid example of a trade name that has thundered all over the world. Of course, this drug is so popular primarily due to its effectiveness, but its unique and easily remembered trade name has greatly contributed to its success.

The drug may be original or generic. The original drug is a completely new, first created product. It has passed a full cycle of preclinical, clinical research. Its active substance is protected by a patent, and huge intellectual and financial resources have been spent on the development, research, production and launch of the pharmaceutical market. Viagra is the original drug from the American pharmaceutical company Pfizer. Upon expiration of the patent, the right to produce another version of the original (generic) can be acquired by any pharmaceutical company. Generic is a drug created by the pharmaceutical “patterns” of the original. In other words, Indian generic Viagra is a copy of a patented medicinal product launched into production at the end of the term of the patent protection of the original drug.

Industrial production of generics is less complicated from a technological point of view, and also much less expensive compared to the production of original products. The cost of long-term clinical studies is not included in the cost of generic Sildenafil – the active substance has already been well studied over the years of use in medical practice.

The requirements for the production of Indian Viagra are absolutely identical and meet all the requirement. In other words, generics are produced using the same standards, principles and rules with regard to equipment for production premises, medicinal raw materials, pharmaceutical personnel, control methods, i.e. all that ultimately ensures the efficiency and safety of the final product. At the same time, the procedure for registration of generics is much cheaper and occurs much faster due to the absence of the need for a full cycle of clinical trials.

To prevent all sorts of speculations around generics, it should be noted that they must be pharmaceutically identical (bioequivalent) to the original. So if you decided to buy generic Viagra, you may be sure it is high quality. Otherwise, the Indian drug would not be allowed for sale.

The availability of bioequivalence between drugs implies a similar bioavailability. Bioavailability is the ability of the active substance to achieve systemic blood flow and the rate at which absorption occurs. If two drugs in equal dose have similar bioavailability, therefore, their efficacy and safety profile will also not significantly differ. There is also therapeutic equivalence, suggesting the possibility of a painless replacement of one drug by another. The main characteristic of a high-quality generic is the therapeutic equivalence achieved by strict quality control of the products. Since pharmaceutical companies may use various substances (including those of dubious origin), outdated technologies, cheap packaging materials in the manufacture of generic drugs, the final product (in our case, generic Viagra from India) may differ from the original in appearance, qualitative and quantitative composition of excipients, pharmacokinetics and pharmacodynamics. As world practice shows, the quality of medicines manufactured by reputable manufacturers is higher. In any case, GMP rules must be strictly observed when producing both originals and generics, and the technological process itself must be controlled by the competent authorities.

How does Indian Viagra work?

During a normal erection, nitric oxide is released in the cavernous body of the penis, activating the guanylate cyclase enzyme. When this enzyme is activated, there is a natural increase in the index of a specific nucleotide and a specific guanosine monophosphate (cGMP). The above nucleotide causes relaxation of the muscles of the cavernous body, increasing the blood supply to the penis.

Sildenafil belongs to the group of selective inhibitors of phosphodiesterase type 5, the action of which stimulates the process of disintegration of cGMP. Thus, sildenafil citrate has an effect on the level of blood supply in the penis. Studies show that in 72% of cases, the product allows you to fully engage in sexual contact. The drug begins to act within one hour after administration, maintaining the effect for 5 hours.

The drug is rapidly absorbed, and its bioavailability is 41%. It reaches his maximum plasma concentration one hour after ingestion on an empty stomach. Under the influence of alcohol and high-calorie foods, absorption of the drug slows down. When ingested, sildenafil binds to plasma proteins and evenly penetrates the tissues. Reviews of doctors about generic Viagra are mostly positive.

Who cannot use this drug?

The product cannot be used by men who are intolerant and hypersensitive to any of the components of the generic Viagra. It is unacceptable to combine the pills with nitrate-containing drugs. Besides, you cannot use the product if you have a high risk of a sudden drop in blood pressure to life-threatening indicators.

If you do not know for sure whether the preparations you are taking contain nitrates or you do not understand which substances specifically belong to nitrates, you need to consult a doctor.

Besides, you cannot use the product if you have a high risk of a sudden drop in blood pressure to life-threatening indicators.

Sildenafil is also contraindicated for use in minors and women. The best option is to consult a doctor before using this medicine.

Things to remember before taking sildenafil

Only a doctor can determine whether generic sildenafil is suitable for you, and therefore, so be sure to consult with a specialist before you buy medicine. The agent may cause a slight temporary drop in blood pressure. To confirm the diagnosis of erectile dysfunction, the doctor may additionally prescribe a medical examination.

The specialist also determines whether Viagra is safe for health, evaluates the state of the cardiovascular system and other major body systems, the doctor eliminates all possible contraindications and also calculates an individual dosage for each man.

You must inform your doctor about any heart problems, including stenocardia, heart failure, heart attacks, pain behind the sternum, aortic valve narrowing, heart rhythm disturbances, history of stroke, high or low blood pressure.

Also tell your doctor if you have ever suffered from severe vision loss, rare congenital eye diseases, liver or kidney problems, blood disorders, including sickle cell anemia or leukemia, anatomical deformities of the penis, Peyronie’s disease, prolonged painful erection.

Before taking Indian Viagra, you must inform your doctor if you are taking any other drugs, had ulcers or any other bleeding in the past. This information will help a specialist correctly assess the risks and find the best treatment for you.

Benefits of Indian Viagra

The widespread popularity of generic sildenafil is based on the numerous advantages of the drug:

  1. The optimal dosage. One generic pill contains the maximum dose of the active substance, which helps achieve an erection and reduce the recovery periods between sexual intercourse;
  2. Safe formula. Many years have passed the development of the original Viagra and the primary product has many drawbacks. But in the course of extensive clinical studies, with the advent of new pharmacological technologies and the improvement of production methods, a safe formula appeared that rarely causes adverse reactions;
  3. Affordable cost. Unlike a brand-name drug, the price of the generic drugs does not include the cost of developing, testing and advertising the brand. Therefore, high-quality Indian Sildenafil can be purchased by every man, regardless of his financial situation.